CD31 (PECAM-1) Proteins

CD31 (PECAM-1) Human recombinant proteins are validated for use in the following applications: Bioactivity and Neutralization. These proteins are expressed in E. coli and HEK293 cells. Available Product Grades: Research Use Only. Our Gibco brand includes SKUs from PeproTech™, acquired by... CD31 (PECAM-1) Human recombinant proteins are validated for use in the following applications: Bioactivity and Neutralization. These proteins are expressed in E. coli and HEK293 cells. Available Product Grades: Research Use Only. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 2 proteins, including... CD31 (PECAM-1) Human recombinant proteins are validated for use in the following applications: Bioactivity and Neutralization. These proteins are expressed in E. coli and HEK293 cells. Available Product Grades: Research Use Only. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 2 proteins, including biologically active options. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... CD31 (PECAM-1) Human recombinant proteins are validated for use in the following applications: Bioactivity and Neutralization. These proteins are expressed in E. coli and HEK293 cells. Available Product Grades: Research Use Only. Our Gibco brand includes SKUs from PeproTech™, acquired by Thermo Fisher Scientific. Browse all 2 proteins, including biologically active options. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

Synonyms

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

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Gibco

Human PECAM-1 Recombinant Protein, PeproTech®

Gibco

Human PECAM-1 Recombinant Protein, PeproTech®

Species

Human

Expression System

HEK293 cells

Product Grade

Research Use Only

Application

Ctrl Bioactivity

Price

Cat # 150-06-50UG

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CD31 (PECAM-1) Proteins

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